The Safety of Drugs Used in Acid-related Disorders and Functional Gastrointestinal Disorders

Neehar Parikh, Colin Howden

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

Medicines are frequently used in the management of acid-related disorders and functional gastrointestinal disorders. With the exception of complicated peptic ulcer disease, these disorders are not associated with appreciable mortality. Drug treatments have consequently been held to the highest standards of safety. Some medicines have been withdrawn or restricted based on assessments and perceptions of risk. However, the risk of serious toxicity is low for most of the agents discussed in this article. Assessments are made of the safety and adverse-event profiles of certain drug classes and, where appropriate, individual medicines. For conditions with a low risk of mortality or serious morbidity, clinicians need to balance the risks of potential adverse events with the anticipated benefits of a successful outcome of specific drug treatment.

Original languageEnglish (US)
Pages (from-to)529-542
Number of pages14
JournalGastroenterology Clinics of North America
Volume39
Issue number3
DOIs
StatePublished - Sep 1 2010

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Gastrointestinal Diseases
Safety
Acids
Pharmaceutical Preparations
Mortality
Peptic Ulcer
Morbidity

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

The Safety of Drugs Used in Acid-related Disorders and Functional Gastrointestinal Disorders. / Parikh, Neehar; Howden, Colin.

In: Gastroenterology Clinics of North America, Vol. 39, No. 3, 01.09.2010, p. 529-542.

Research output: Contribution to journalReview article

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