The transformation of nitriles into amides using sodium percarbonate

George Kabalka, Sunil M. Deshpande, Prakash P. Wadgaonkar, Narayana Chatla

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The usefulness of sodium Dercarbonate. an inexoen- sive, safe and easily handled reagent for the transformation of nitriles into amides was investigated. Aromatic nitriles lacking ortho-substituents and heteroaromatic nitriles were efficiently transformed into amides; while ortho-substituted aromatic nitriles and aliphatic nitriles gave moderate yields of the corresponding amides.

Original languageEnglish (US)
Pages (from-to)1445-1451
Number of pages7
JournalSynthetic Communications
Volume20
Issue number10
DOIs
StatePublished - Jan 1 1990

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Nitriles
Amides
Sodium
sodium percarbonate

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

The transformation of nitriles into amides using sodium percarbonate. / Kabalka, George; Deshpande, Sunil M.; Wadgaonkar, Prakash P.; Chatla, Narayana.

In: Synthetic Communications, Vol. 20, No. 10, 01.01.1990, p. 1445-1451.

Research output: Contribution to journalArticle

Kabalka, George ; Deshpande, Sunil M. ; Wadgaonkar, Prakash P. ; Chatla, Narayana. / The transformation of nitriles into amides using sodium percarbonate. In: Synthetic Communications. 1990 ; Vol. 20, No. 10. pp. 1445-1451.
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