The use of potassium alkynyltrifluoroborates in Mannich reactions

George Kabalka, Bollu Venkataiah, Gang Dong

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Potassium alkynyltrifluoroborates react with amines and salicylaldehydes in the presence of benzoic acid to generate highly functionalized amines. Ionic liquids such as butylmethylimidazolium tetrafluoroborate (BmimBF4) are suitable solvents for the reaction.

Original languageEnglish (US)
Pages (from-to)729-731
Number of pages3
JournalTetrahedron Letters
Volume45
Issue number4
DOIs
StatePublished - Jan 19 2004

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Amines
Potassium
Ionic Liquids
Benzoic Acid
salicylaldehyde

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

The use of potassium alkynyltrifluoroborates in Mannich reactions. / Kabalka, George; Venkataiah, Bollu; Dong, Gang.

In: Tetrahedron Letters, Vol. 45, No. 4, 19.01.2004, p. 729-731.

Research output: Contribution to journalArticle

Kabalka, George ; Venkataiah, Bollu ; Dong, Gang. / The use of potassium alkynyltrifluoroborates in Mannich reactions. In: Tetrahedron Letters. 2004 ; Vol. 45, No. 4. pp. 729-731.
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