The usefulness of 0.45 μm-rated filter membranes

A. Mark Trotter, Patrick J. Rodrigues, Laura A. Thoma

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This study examines the retention of Brevundimonas diminuta (B. diminuta, ATCC 19146) by four different types of 0.45 μm-rated membranes at two differential test pressures, 5 and 30 psi. The results demonstrated the ability of 0.45 μm-rated filter membranes to retain at least 1 × 103 organisms at 5 psi and > 1 × 108 organisms at differential pressures of 30 psi. These findings, in addition to those referenced here, indicate that the 0.45 μm-rated filters can serve as sterilizing and bioburden reduction filters when challenged with significant numbers, 1 × 108 cfu/cm2 of B. diminuta in a wide range of differential pressures.

Original languageEnglish (US)
Pages (from-to)60-70
Number of pages11
JournalPharmaceutical Technology North America
Volume26
Issue number4
StatePublished - Jan 1 2002

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Pressure
Membranes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Pharmaceutical Science

Cite this

Trotter, A. M., Rodrigues, P. J., & Thoma, L. A. (2002). The usefulness of 0.45 μm-rated filter membranes. Pharmaceutical Technology North America, 26(4), 60-70.

The usefulness of 0.45 μm-rated filter membranes. / Trotter, A. Mark; Rodrigues, Patrick J.; Thoma, Laura A.

In: Pharmaceutical Technology North America, Vol. 26, No. 4, 01.01.2002, p. 60-70.

Research output: Contribution to journalArticle

Trotter, AM, Rodrigues, PJ & Thoma, LA 2002, 'The usefulness of 0.45 μm-rated filter membranes', Pharmaceutical Technology North America, vol. 26, no. 4, pp. 60-70.
Trotter AM, Rodrigues PJ, Thoma LA. The usefulness of 0.45 μm-rated filter membranes. Pharmaceutical Technology North America. 2002 Jan 1;26(4):60-70.
Trotter, A. Mark ; Rodrigues, Patrick J. ; Thoma, Laura A. / The usefulness of 0.45 μm-rated filter membranes. In: Pharmaceutical Technology North America. 2002 ; Vol. 26, No. 4. pp. 60-70.
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