Three-dimensional focus of attention for iterative cone-beam micro-CT reconstruction

T. M. Benson, Jens Gregor

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Three-dimensional iterative reconstruction of high-resolution, circular orbit cone-beam x-ray CT data is often considered impractical due to the demand for vast amounts of computer cycles and associated memory. In this paper, we show that the computational burden can be reduced by limiting the reconstruction to a small, well-defined portion of the image volume. We first discuss using the support region defined by the set of voxels covered by all of the projection views. We then present a data-driven preprocessing technique called focus of attention that heuristically separates both image and projection data into object and background before reconstruction, thereby further reducing the reconstruction region of interest. We present experimental results for both methods based on mouse data and a parallelized implementation of the SIRT algorithm. The computational savings associated with the support region are substantial. However, the results for focus of attention are even more impressive in that only about one quarter of the computer cycles and memory are needed compared with reconstruction of the entire image volume. The image quality is not compromised by either method.

Original languageEnglish (US)
Article number006
Pages (from-to)4533-4546
Number of pages14
JournalPhysics in Medicine and Biology
Volume51
Issue number18
DOIs
StatePublished - Sep 21 2006
Externally publishedYes

Fingerprint

Cone-Beam Computed Tomography
Cones
cones
Data storage equipment
Computer-Assisted Image Processing
Orbit
Image quality
Orbits
X-Rays
X rays
projection
cycles
circular orbits
preprocessing
mice
high resolution
x rays

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Three-dimensional focus of attention for iterative cone-beam micro-CT reconstruction. / Benson, T. M.; Gregor, Jens.

In: Physics in Medicine and Biology, Vol. 51, No. 18, 006, 21.09.2006, p. 4533-4546.

Research output: Contribution to journalArticle

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