Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA)

V. K. Sharma, Georgios Tsivgoulis, A. Y. Lao, M. Flaster, J. L. Frey, Marc Malkoff, Andrei Alexandrov

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the 'head-down' position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra-indication to systemic thrombolysis.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalEuropean Journal of Neurology
Volume14
Issue number2
DOIs
StatePublished - Feb 1 2007
Externally publishedYes

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Common Carotid Artery
Tissue Plasminogen Activator
Stroke
Water-Electrolyte Balance
Arteries
Head
Blood Pressure
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA). / Sharma, V. K.; Tsivgoulis, Georgios; Lao, A. Y.; Flaster, M.; Frey, J. L.; Malkoff, Marc; Alexandrov, Andrei.

In: European Journal of Neurology, Vol. 14, No. 2, 01.02.2007, p. 237-240.

Research output: Contribution to journalArticle

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