Time-locked brain activity associated with emotion: A pilot MEG study

Jose Leon-Carrion, Mark H. McManis, Eduardo M. Castillo, Andrew Papanicolaou

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To examine the time course of brain activation in response to emotionally evocative pictures. Methods and procedures: Regions of the brain involved in the processing of affective stimuli in response to picture sets rated unpleasant, pleasant and affectively neutral, as well as the order of activation of each region, were investigated using magnetoencephalography in 10 normal adult volunteers. Results: Spatiotemporal maps were found consisting of two basic components. The first involving activation in the occipital and basal aspects of the temporal cortex- lasted, on average, 270 ms post-stimulus. The second component involving activation in the mesial temporal lobes (MTL) extended from 270 to 850 ms post-stimulus. After (serial) activating the mesial temporal lobe structures or simultaneous (parallel) to it, activation is also observed in the frontal structures. Conclusions: The temporal organization in the brain of an emotional stimulus requires the serial and alternating engagement of frontal and posterior cortices. It is suggested that lesions to the brain may disrupt this temporal course, altering the emotional response commonly observed in patients with brain injury.

Original languageEnglish (US)
Pages (from-to)857-865
Number of pages9
JournalBrain Injury
Volume20
Issue number8
DOIs
StatePublished - Jan 1 2006

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Emotions
Temporal Lobe
Brain
Magnetoencephalography
Frontal Lobe
Brain Injuries
Healthy Volunteers
Activation
Emotion
Stimulus
Cortex

All Science Journal Classification (ASJC) codes

  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Leon-Carrion, J., McManis, M. H., Castillo, E. M., & Papanicolaou, A. (2006). Time-locked brain activity associated with emotion: A pilot MEG study. Brain Injury, 20(8), 857-865. https://doi.org/10.1080/02699050600832304

Time-locked brain activity associated with emotion : A pilot MEG study. / Leon-Carrion, Jose; McManis, Mark H.; Castillo, Eduardo M.; Papanicolaou, Andrew.

In: Brain Injury, Vol. 20, No. 8, 01.01.2006, p. 857-865.

Research output: Contribution to journalArticle

Leon-Carrion, J, McManis, MH, Castillo, EM & Papanicolaou, A 2006, 'Time-locked brain activity associated with emotion: A pilot MEG study', Brain Injury, vol. 20, no. 8, pp. 857-865. https://doi.org/10.1080/02699050600832304
Leon-Carrion J, McManis MH, Castillo EM, Papanicolaou A. Time-locked brain activity associated with emotion: A pilot MEG study. Brain Injury. 2006 Jan 1;20(8):857-865. https://doi.org/10.1080/02699050600832304
Leon-Carrion, Jose ; McManis, Mark H. ; Castillo, Eduardo M. ; Papanicolaou, Andrew. / Time-locked brain activity associated with emotion : A pilot MEG study. In: Brain Injury. 2006 ; Vol. 20, No. 8. pp. 857-865.
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