Treatment modification of yttrium-90 radioembolization based on quantitative positron emission tomography/CT imaging

Ted T. Chang, Austin Bourgeois, Anastasia M. Balius, Alexander Pasciak

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Treatment activity for yttrium-90 (90Y) radioembolization when calculated by using the manufacturer-recommended technique is only partially patient-specific and may result in a subtumoricidal dose in some patients. The authors describe the use of quantitative 90Y positron emission tomography/computed tomography as a tool to provide patient-specific optimization of treatment activity and evaluate this new method in a patient who previously received traditional 90Y radioembolization. The modified treatment resulted in a 40-Gy increase in absorbed dose to tumor and complete resolution of disease in the treated area within 3 months.

Original languageEnglish (US)
Pages (from-to)333-337
Number of pages5
JournalJournal of Vascular and Interventional Radiology
Volume24
Issue number3
DOIs
StatePublished - Mar 1 2013
Externally publishedYes

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Yttrium
Positron-Emission Tomography
Therapeutics
Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Treatment modification of yttrium-90 radioembolization based on quantitative positron emission tomography/CT imaging. / Chang, Ted T.; Bourgeois, Austin; Balius, Anastasia M.; Pasciak, Alexander.

In: Journal of Vascular and Interventional Radiology, Vol. 24, No. 3, 01.03.2013, p. 333-337.

Research output: Contribution to journalArticle

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