Treatment of attention deficit hyperactivity disorder: A critical review

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This review evaluates the treatment of attention deficit hyperactivity disorder. Current evidence supports the belief that stimulants are the most effective and least toxic of the drugs used in the treatment of hyperactivity. Tricyclic antidepressants (TCAs), however, are preferable in subpopulations with concomitant anxiety or depressive disorders. Studies comparing stimulants with TCAs are evaluated and studies that have examined other antidepressants are summarized. In addition, TCAs and stimulants are compared according to adverse-effect profiles, pharmacokinetic properties, and subgroup responses. Based on these data and the recently reported sudden deaths in children receiving desipramine, treatment recommendations are made.

Original languageEnglish (US)
Pages (from-to)1207-1213
Number of pages7
JournalAnnals of Pharmacotherapy
Volume25
Issue number11
DOIs
StatePublished - Jan 1 1991

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Tricyclic Antidepressive Agents
Attention Deficit Disorder with Hyperactivity
Desipramine
Poisons
Depressive Disorder
Sudden Death
Anxiety Disorders
Antidepressive Agents
Therapeutics
Pharmacokinetics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Treatment of attention deficit hyperactivity disorder : A critical review. / Brown, Candace.

In: Annals of Pharmacotherapy, Vol. 25, No. 11, 01.01.1991, p. 1207-1213.

Research output: Contribution to journalArticle

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