Treatment of bisphosphonates-associated osteonecrosis

Cesar A. Migliorati, Wendy S. Hupp, Erica K.J. Migliorati

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagnosed. During the description of each aspect of the case, a discussion of the rationale used for the case management is presented with support of the available literature. Aspects of interest include the diagnosis of BON, the risk factor for BON for this particular patient, the decision making process for the management of acute and long-term oral cavity problems, and the introduction of high intensity laser therapy to help control pain and reduce infection and local bacterial load.

Original languageEnglish (US)
Pages (from-to)62-68
Number of pages7
JournalClinical Cases in Mineral and Bone Metabolism
Volume4
Issue number1
StatePublished - Jan 1 2007

Fingerprint

Bisphosphonate-Associated Osteonecrosis of the Jaw
zoledronic acid
Bone Neoplasms
Bacterial Load
Metabolic Bone Diseases
Bone Diseases
Case Management
Laser Therapy
Therapeutics
Mouth
Neoplasms
Prostatic Neoplasms
Decision Making
Pain
Infection

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Migliorati, C. A., Hupp, W. S., & Migliorati, E. K. J. (2007). Treatment of bisphosphonates-associated osteonecrosis. Clinical Cases in Mineral and Bone Metabolism, 4(1), 62-68.

Treatment of bisphosphonates-associated osteonecrosis. / Migliorati, Cesar A.; Hupp, Wendy S.; Migliorati, Erica K.J.

In: Clinical Cases in Mineral and Bone Metabolism, Vol. 4, No. 1, 01.01.2007, p. 62-68.

Research output: Contribution to journalShort survey

Migliorati, CA, Hupp, WS & Migliorati, EKJ 2007, 'Treatment of bisphosphonates-associated osteonecrosis', Clinical Cases in Mineral and Bone Metabolism, vol. 4, no. 1, pp. 62-68.
Migliorati CA, Hupp WS, Migliorati EKJ. Treatment of bisphosphonates-associated osteonecrosis. Clinical Cases in Mineral and Bone Metabolism. 2007 Jan 1;4(1):62-68.
Migliorati, Cesar A. ; Hupp, Wendy S. ; Migliorati, Erica K.J. / Treatment of bisphosphonates-associated osteonecrosis. In: Clinical Cases in Mineral and Bone Metabolism. 2007 ; Vol. 4, No. 1. pp. 62-68.
@article{cf6082be4f6a46d7848e9f0a921dbca2,
title = "Treatment of bisphosphonates-associated osteonecrosis",
abstract = "This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagnosed. During the description of each aspect of the case, a discussion of the rationale used for the case management is presented with support of the available literature. Aspects of interest include the diagnosis of BON, the risk factor for BON for this particular patient, the decision making process for the management of acute and long-term oral cavity problems, and the introduction of high intensity laser therapy to help control pain and reduce infection and local bacterial load.",
author = "Migliorati, {Cesar A.} and Hupp, {Wendy S.} and Migliorati, {Erica K.J.}",
year = "2007",
month = "1",
day = "1",
language = "English (US)",
volume = "4",
pages = "62--68",
journal = "Clinical Cases in Mineral and Bone Metabolism",
issn = "1724-8914",
publisher = "CIC Edizioni Internazionali s.r.l.",
number = "1",

}

TY - JOUR

T1 - Treatment of bisphosphonates-associated osteonecrosis

AU - Migliorati, Cesar A.

AU - Hupp, Wendy S.

AU - Migliorati, Erica K.J.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagnosed. During the description of each aspect of the case, a discussion of the rationale used for the case management is presented with support of the available literature. Aspects of interest include the diagnosis of BON, the risk factor for BON for this particular patient, the decision making process for the management of acute and long-term oral cavity problems, and the introduction of high intensity laser therapy to help control pain and reduce infection and local bacterial load.

AB - This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagnosed. During the description of each aspect of the case, a discussion of the rationale used for the case management is presented with support of the available literature. Aspects of interest include the diagnosis of BON, the risk factor for BON for this particular patient, the decision making process for the management of acute and long-term oral cavity problems, and the introduction of high intensity laser therapy to help control pain and reduce infection and local bacterial load.

UR - http://www.scopus.com/inward/record.url?scp=34250337338&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250337338&partnerID=8YFLogxK

M3 - Short survey

VL - 4

SP - 62

EP - 68

JO - Clinical Cases in Mineral and Bone Metabolism

JF - Clinical Cases in Mineral and Bone Metabolism

SN - 1724-8914

IS - 1

ER -