Treatment Strategies for Myoclonic Seizures and Epilepsy Syndromes with Myoclonic Seizures

James Wheless, Raman Sankar

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Despite the availability of numerous treatment options, the diagnosis and treatment of myoclonic seizures continue to be challenging. Based on clinical experience, valproate and benzodiazepines have historically been used to treat myoclonic seizures. However, many more treatment options exist today, and the clinician must match the appropriate treatment with the patient's epilepsy syndrome and its underlying etiology. Comorbidities and other medications must also be considered when making decisions regarding treatment. Rarely, some antiepileptic drugs may exacerbate myoclonic seizures. Most epileptic myoclonus can be treated pharmacologically, but some cases respond better to surgery, the ketogenic diet, or vagus nerve stimulation. Because myoclonic seizures can be difficult to treat, clinicians should be flexible in their approach and tailor therapy to each patient.

Original languageEnglish (US)
Pages (from-to)27-37
Number of pages11
JournalEpilepsia
Volume44
Issue numberSUPPL. 11
DOIs
StatePublished - Jan 1 2003
Externally publishedYes

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Myoclonic Epilepsy
Seizures
Therapeutics
Ketogenic Diet
Vagus Nerve Stimulation
Myoclonus
Valproic Acid
Benzodiazepines
Anticonvulsants
Comorbidity
Epilepsy
Decision Making

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Treatment Strategies for Myoclonic Seizures and Epilepsy Syndromes with Myoclonic Seizures. / Wheless, James; Sankar, Raman.

In: Epilepsia, Vol. 44, No. SUPPL. 11, 01.01.2003, p. 27-37.

Research output: Contribution to journalArticle

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