Two patterns of firing in human neocortical neurons

Robert Foehring, A. R. Wyler

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Intracellular recordings were made in slices of human neocortex removed for surgical treatment of epilepsy. In response to prolonged suprathreshold current injection, regular spiking neurons (67.5% of sample) responded by repetitive firing throughout the stimulus from all membrane potentials. Bursting neurons (32.5% of sample) responded with a burst of 2-3 spikes which rode upon a voltage-dependent slow depolarization. Bursting behavior was only observed from membrane potentials more negative than -65 mV.

Original languageEnglish (US)
Pages (from-to)279-285
Number of pages7
JournalNeuroscience Letters
Volume110
Issue number3
DOIs
StatePublished - Mar 14 1990

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Membrane Potentials
Neurons
Neocortex
Epilepsy
Injections
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Two patterns of firing in human neocortical neurons. / Foehring, Robert; Wyler, A. R.

In: Neuroscience Letters, Vol. 110, No. 3, 14.03.1990, p. 279-285.

Research output: Contribution to journalArticle

Foehring, Robert ; Wyler, A. R. / Two patterns of firing in human neocortical neurons. In: Neuroscience Letters. 1990 ; Vol. 110, No. 3. pp. 279-285.
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