Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma: Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait

Piergiuseppe Colombo, Steven C. Smith, Simona Massa, Salvatore L. Renne, Simona Brambilla, Roberto Peschechera, Pierpaolo Graziotti, Massimo Roncalli, Mahul Amin

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature. The tumor demonstrated features associated with renal medullary carcinoma, or unclassified renal cell carcinoma, medullary phenotype as recently described; the presence of sickle cell trait confirmed the diagnosis of medullary carcinoma. This case is helpful in the differential diagnosis with non-sickle cell associated "renal cell carcinoma, unclassified with medullary phenotype," and study of this spectrum of tumors is ongoing.

Original languageEnglish (US)
Pages (from-to)215-218
Number of pages4
JournalUrology Case Reports
Volume3
Issue number6
DOIs
StatePublished - Nov 1 2015

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Sickle Cell Trait
Medullary Carcinoma
Renal Cell Carcinoma
Phenotype
Kidney
Neoplasms
Differential Diagnosis
Carcinoma

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma : Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait. / Colombo, Piergiuseppe; Smith, Steven C.; Massa, Simona; Renne, Salvatore L.; Brambilla, Simona; Peschechera, Roberto; Graziotti, Pierpaolo; Roncalli, Massimo; Amin, Mahul.

In: Urology Case Reports, Vol. 3, No. 6, 01.11.2015, p. 215-218.

Research output: Contribution to journalArticle

Colombo, Piergiuseppe ; Smith, Steven C. ; Massa, Simona ; Renne, Salvatore L. ; Brambilla, Simona ; Peschechera, Roberto ; Graziotti, Pierpaolo ; Roncalli, Massimo ; Amin, Mahul. / Unclassified Renal Cell Carcinoma With Medullary Phenotype Versus Renal Medullary Carcinoma : Lessons From Diagnosis in an Italian Man Found to Harbor Sickle Cell Trait. In: Urology Case Reports. 2015 ; Vol. 3, No. 6. pp. 215-218.
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