Unilateral sporadic retinoblastoma presenting as acute secondary glaucoma with intraocular inflammation

Theresa R. Kramer, Todd M. Watanabe, Joseph M. Miller, Matthew Wilson, Richard R. Ober

Research output: Contribution to journalArticle

Abstract

We describe a case of unilateral sporadic retinoblastoma presenting as intraocular inflammation and secondary acute glaucoma in a six-year-old boy. Fine-needle aspiration biopsy (FNAB) of the anterior chamber was needed to confirm the diagnosis as both B-scan ultrasonography and computerized tomography (CT) revealed no intraocular mass or calcifications. Enucleation was performed. Histopathology showed a diffuse infiltrating retinoblastoma with involvement of the trabecular meshwork and Schlemm's canal. Because of the extensive duration of symptoms, the identification of tumor cells in Schlemm's canal/collector channels indicating possible extraocular extension, the patient received prophylactic chemotherapy. The patient has had no recurrence 24 months following treatment.

Original languageEnglish (US)
Pages (from-to)201-207
Number of pages7
JournalClinical and Surgical Ophthalmology
Volume26
Issue number6
StatePublished - Jun 2008
Externally publishedYes

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Retinoblastoma
Glaucoma
Inflammation
Trabecular Meshwork
Anterior Chamber
Fine Needle Biopsy
Ultrasonography
Tomography
Recurrence
Drug Therapy
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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Unilateral sporadic retinoblastoma presenting as acute secondary glaucoma with intraocular inflammation. / Kramer, Theresa R.; Watanabe, Todd M.; Miller, Joseph M.; Wilson, Matthew; Ober, Richard R.

In: Clinical and Surgical Ophthalmology, Vol. 26, No. 6, 06.2008, p. 201-207.

Research output: Contribution to journalArticle

Kramer, Theresa R. ; Watanabe, Todd M. ; Miller, Joseph M. ; Wilson, Matthew ; Ober, Richard R. / Unilateral sporadic retinoblastoma presenting as acute secondary glaucoma with intraocular inflammation. In: Clinical and Surgical Ophthalmology. 2008 ; Vol. 26, No. 6. pp. 201-207.
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