Update on neuroblastoma

On behalf of the APSA Cancer committee

Research output: Contribution to journalReview article

Abstract

Neuroblastoma is an embryonic cancer arising from neural crest stem cells. This cancer is the most common malignancy in infants and the most common extracranial solid tumor in children. The clinical course may be highly variable with the possibility of spontaneous regression in the youngest patients and increased risk of aggressive disease in older children. Clinical heterogeneity is a consequence of the diverse biologic characteristics that determine patient risk and survival. This review will focus on current progress in neuroblastoma staging, risk stratification, and treatment strategies based on advancing knowledge in tumor biology and genetic characterization. Type of study: Review article. Level of evidence: Level II.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalJournal of pediatric surgery
Volume54
Issue number3
DOIs
StatePublished - Mar 1 2019

Fingerprint

Neuroblastoma
Neoplasms
Neural Stem Cells
Neural Crest
Survival
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

On behalf of the APSA Cancer committee (2019). Update on neuroblastoma. Journal of pediatric surgery, 54(3), 383-389. https://doi.org/10.1016/j.jpedsurg.2018.09.004

Update on neuroblastoma. / On behalf of the APSA Cancer committee.

In: Journal of pediatric surgery, Vol. 54, No. 3, 01.03.2019, p. 383-389.

Research output: Contribution to journalReview article

On behalf of the APSA Cancer committee 2019, 'Update on neuroblastoma', Journal of pediatric surgery, vol. 54, no. 3, pp. 383-389. https://doi.org/10.1016/j.jpedsurg.2018.09.004
On behalf of the APSA Cancer committee. Update on neuroblastoma. Journal of pediatric surgery. 2019 Mar 1;54(3):383-389. https://doi.org/10.1016/j.jpedsurg.2018.09.004
On behalf of the APSA Cancer committee. / Update on neuroblastoma. In: Journal of pediatric surgery. 2019 ; Vol. 54, No. 3. pp. 383-389.
@article{f5b0e73381124ff49c66f62661c702c9,
title = "Update on neuroblastoma",
abstract = "Neuroblastoma is an embryonic cancer arising from neural crest stem cells. This cancer is the most common malignancy in infants and the most common extracranial solid tumor in children. The clinical course may be highly variable with the possibility of spontaneous regression in the youngest patients and increased risk of aggressive disease in older children. Clinical heterogeneity is a consequence of the diverse biologic characteristics that determine patient risk and survival. This review will focus on current progress in neuroblastoma staging, risk stratification, and treatment strategies based on advancing knowledge in tumor biology and genetic characterization. Type of study: Review article. Level of evidence: Level II.",
author = "{On behalf of the APSA Cancer committee} and Newman, {Erika A.} and Shahab Abdessalam and Aldrink, {Jennifer H.} and Mary Austin and Heaton, {Todd E.} and Jennifer Bruny and Peter Ehrlich and Roshni Dasgupta and Baertschiger, {Reto M.} and Lautz, {Timothy B.} and Rhee, {Daniel S.} and Max Langham and Malek, {Marcus M.} and Meyers, {Rebecka L.} and Nathan, {Jaimie D.} and Weil, {Brent R.} and Stephanie Polites and Madonna, {Mary Beth}",
year = "2019",
month = "3",
day = "1",
doi = "10.1016/j.jpedsurg.2018.09.004",
language = "English (US)",
volume = "54",
pages = "383--389",
journal = "Journal of Pediatric Surgery",
issn = "0022-3468",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Update on neuroblastoma

AU - On behalf of the APSA Cancer committee

AU - Newman, Erika A.

AU - Abdessalam, Shahab

AU - Aldrink, Jennifer H.

AU - Austin, Mary

AU - Heaton, Todd E.

AU - Bruny, Jennifer

AU - Ehrlich, Peter

AU - Dasgupta, Roshni

AU - Baertschiger, Reto M.

AU - Lautz, Timothy B.

AU - Rhee, Daniel S.

AU - Langham, Max

AU - Malek, Marcus M.

AU - Meyers, Rebecka L.

AU - Nathan, Jaimie D.

AU - Weil, Brent R.

AU - Polites, Stephanie

AU - Madonna, Mary Beth

PY - 2019/3/1

Y1 - 2019/3/1

N2 - Neuroblastoma is an embryonic cancer arising from neural crest stem cells. This cancer is the most common malignancy in infants and the most common extracranial solid tumor in children. The clinical course may be highly variable with the possibility of spontaneous regression in the youngest patients and increased risk of aggressive disease in older children. Clinical heterogeneity is a consequence of the diverse biologic characteristics that determine patient risk and survival. This review will focus on current progress in neuroblastoma staging, risk stratification, and treatment strategies based on advancing knowledge in tumor biology and genetic characterization. Type of study: Review article. Level of evidence: Level II.

AB - Neuroblastoma is an embryonic cancer arising from neural crest stem cells. This cancer is the most common malignancy in infants and the most common extracranial solid tumor in children. The clinical course may be highly variable with the possibility of spontaneous regression in the youngest patients and increased risk of aggressive disease in older children. Clinical heterogeneity is a consequence of the diverse biologic characteristics that determine patient risk and survival. This review will focus on current progress in neuroblastoma staging, risk stratification, and treatment strategies based on advancing knowledge in tumor biology and genetic characterization. Type of study: Review article. Level of evidence: Level II.

UR - http://www.scopus.com/inward/record.url?scp=85054462809&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054462809&partnerID=8YFLogxK

U2 - 10.1016/j.jpedsurg.2018.09.004

DO - 10.1016/j.jpedsurg.2018.09.004

M3 - Review article

VL - 54

SP - 383

EP - 389

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

SN - 0022-3468

IS - 3

ER -