Update on Rifampin Drug Interactions

Anne M. Baciewicz, Timothy Self, William B. Bekemeyer

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Rifampin, a potent inducer of the hepatic microsomal system, has been shown to cause clinically important interactions when combined with other drugs, including oral anticoagulants, oral contraceptives, digitoxin, methadone hydrochloride, sulfonylureas, and barbiturates. Additional literature on previously described interactions has been published recently on quinidine, glucocorticoids, digoxin, and theophylline. New rifampin interactions have been described for cyclosporine, ketoconazole, chloramphenicol, β-blockers, verapamil, and phenytoin. These interactions seem to be of clinical significance.

Original languageEnglish (US)
Pages (from-to)565-568
Number of pages4
JournalArchives of Internal Medicine
Volume147
Issue number3
DOIs
StatePublished - Jan 1 1987

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Rifampin
Drug Interactions
Digitoxin
Barbiturates
Quinidine
Ketoconazole
Digoxin
Methadone
Phenytoin
Chloramphenicol
Theophylline
Oral Contraceptives
Verapamil
Anticoagulants
Cyclosporine
Glucocorticoids
Liver
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Update on Rifampin Drug Interactions. / Baciewicz, Anne M.; Self, Timothy; Bekemeyer, William B.

In: Archives of Internal Medicine, Vol. 147, No. 3, 01.01.1987, p. 565-568.

Research output: Contribution to journalArticle

Baciewicz, AM, Self, T & Bekemeyer, WB 1987, 'Update on Rifampin Drug Interactions', Archives of Internal Medicine, vol. 147, no. 3, pp. 565-568. https://doi.org/10.1001/archinte.1987.00370030169033
Baciewicz, Anne M. ; Self, Timothy ; Bekemeyer, William B. / Update on Rifampin Drug Interactions. In: Archives of Internal Medicine. 1987 ; Vol. 147, No. 3. pp. 565-568.
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