Update on the management of hypertension: Is there a difference in the treatment of hypertension in the elderly, diabetics, and African Americans?

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Abstract

What do we know about the treatment of hypertension in the elderly, in diabetics, and in African Americans (especially in light of what we have come to call evidence-based medicine)? When we are giving drugs to patients, everyday over many months and years, we need to analyze the long term effects of these drugs; we have not always done that. It is important to realize that the U.S. FDA has approved most of our antihypertensive agents based on its efficacy in lowering blood pressure (BP) and safety over several months to a year, not based on effects on major cardiovascular events over several years. In light of this, which antihypertensive drugs have shown long term evidence of benefit and safety in the elderly, diabetics, and African Americans, and are there differences in which drugs should be used or how aggressive hypertension should be treated in these groups?.

Original languageEnglish (US)
Pages (from-to)291-296
Number of pages6
JournalCardiovascular Reviews and Reports
Volume20
Issue number5
StatePublished - May 1 1999
Externally publishedYes

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African Americans
Hypertension
Antihypertensive Agents
Pharmaceutical Preparations
Blood Safety
Evidence-Based Medicine
Therapeutics
Blood Pressure
Safety

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Update on the management of hypertension: Is there a difference in the treatment of hypertension in the elderly, diabetics, and African Americans?",
abstract = "What do we know about the treatment of hypertension in the elderly, in diabetics, and in African Americans (especially in light of what we have come to call evidence-based medicine)? When we are giving drugs to patients, everyday over many months and years, we need to analyze the long term effects of these drugs; we have not always done that. It is important to realize that the U.S. FDA has approved most of our antihypertensive agents based on its efficacy in lowering blood pressure (BP) and safety over several months to a year, not based on effects on major cardiovascular events over several years. In light of this, which antihypertensive drugs have shown long term evidence of benefit and safety in the elderly, diabetics, and African Americans, and are there differences in which drugs should be used or how aggressive hypertension should be treated in these groups?.",
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