Update on the use of distal radial bone density measurements in prediction of hip and Colles' fracture risk

Gayle E. Lester, John J.B. Anderson, Frances Tylavsky, William R. Sutton, Sandra S. Stinnett, Ralph A. DeMasi, Roy V. Talmage

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A controversy has developed around the question as to whether bone density values from the distal radius can be used to accurately predict risk of future fractures. To address this question, two separate studies were undertaken: (a) Bone density was measured in 460 healthy ambulatory women living in retirement centers in the state of North Carolina; 83% of these women were followed for up to 60 months for occurrence of minimal trauma hip and wrist fractures. Thirty‐one minimal trauma fractures were reported in our study population, representing 8% of those followed. The fracture incidence density rate‐showed a close inverse relationship with incremental changes in bone density at the distal site. Twenty‐eight of the 31 fractures were reported in women with bone density values below the 325‐mg/cm2 “at risk” value. (b) Bone density values of the distal radius and the lumbar spine from 360 women (aged 18–85 years) from the Chapel Hill area were used to analyze the error in predicting individual spinal density from the distal radial density. Although the overall correlation was high (r = 0.67) and the confidence intervals were narrow, the prediction intervals were quite wide. Thus, prediction of an individual value of spine density from the distal radius density would result in a value with a range too wide to be clinically useful. We conclude that singlephoton absorptiometry appears to be a useful tool for screening normal populations of asymptomatic women for prediction of hip or Colles' fracture risk or individual values for spinal density.

Original languageEnglish (US)
Pages (from-to)220-226
Number of pages7
JournalJournal of Orthopaedic Research
Volume8
Issue number2
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

Fingerprint

Colles' Fracture
Hip Fractures
Bone Density
Spine
Retirement
Wounds and Injuries
Wrist
Population
Hip
Confidence Intervals
Incidence

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine

Cite this

Update on the use of distal radial bone density measurements in prediction of hip and Colles' fracture risk. / Lester, Gayle E.; Anderson, John J.B.; Tylavsky, Frances; Sutton, William R.; Stinnett, Sandra S.; DeMasi, Ralph A.; Talmage, Roy V.

In: Journal of Orthopaedic Research, Vol. 8, No. 2, 01.01.1990, p. 220-226.

Research output: Contribution to journalArticle

Lester, Gayle E. ; Anderson, John J.B. ; Tylavsky, Frances ; Sutton, William R. ; Stinnett, Sandra S. ; DeMasi, Ralph A. ; Talmage, Roy V. / Update on the use of distal radial bone density measurements in prediction of hip and Colles' fracture risk. In: Journal of Orthopaedic Research. 1990 ; Vol. 8, No. 2. pp. 220-226.
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abstract = "A controversy has developed around the question as to whether bone density values from the distal radius can be used to accurately predict risk of future fractures. To address this question, two separate studies were undertaken: (a) Bone density was measured in 460 healthy ambulatory women living in retirement centers in the state of North Carolina; 83{\%} of these women were followed for up to 60 months for occurrence of minimal trauma hip and wrist fractures. Thirty‐one minimal trauma fractures were reported in our study population, representing 8{\%} of those followed. The fracture incidence density rate‐showed a close inverse relationship with incremental changes in bone density at the distal site. Twenty‐eight of the 31 fractures were reported in women with bone density values below the 325‐mg/cm2 “at risk” value. (b) Bone density values of the distal radius and the lumbar spine from 360 women (aged 18–85 years) from the Chapel Hill area were used to analyze the error in predicting individual spinal density from the distal radial density. Although the overall correlation was high (r = 0.67) and the confidence intervals were narrow, the prediction intervals were quite wide. Thus, prediction of an individual value of spine density from the distal radius density would result in a value with a range too wide to be clinically useful. We conclude that singlephoton absorptiometry appears to be a useful tool for screening normal populations of asymptomatic women for prediction of hip or Colles' fracture risk or individual values for spinal density.",
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