Ureidosuccinate is transported by the allantoate transport system in Saccharomyces cerevisiae

V. Turoscy, Terrance Cooper

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The regulatory characteristics exhibited by ureidosuccinate transport in Saccharomyces cerevisiae led us to hypothesize that this biosynthetic inter mediate was transported via the degradative allantoate transport system. The hypothesis was verified by the finding that neither dal5 nor urep1 mutant strains could transport allantoate or ureidosuccinate. Mutations in the two loci were tightly linked and failed to complement one another, suggesting that they were allelic. The use of a common transport system for accumulation of both biosynthetic and degradative metabolites explains the paradoxical characteristics observed for control of ureidosuccinate and allantoate transport.

Original languageEnglish (US)
Pages (from-to)2598-2600
Number of pages3
JournalJournal of Bacteriology
Volume169
Issue number6
DOIs
StatePublished - Jan 1 1987

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Saccharomyces cerevisiae
Mutation

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

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Ureidosuccinate is transported by the allantoate transport system in Saccharomyces cerevisiae. / Turoscy, V.; Cooper, Terrance.

In: Journal of Bacteriology, Vol. 169, No. 6, 01.01.1987, p. 2598-2600.

Research output: Contribution to journalArticle

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