US pharmacists' effect as team members on patient care: Systematic review and meta-analyses

Marie Chisholm-Burns, Jeannie Kim Lee, Christina Spivey, Marion Slack, Richard N. Herrier, Elizabeth Hall-Lipsy, Joshua Graff Zivin, Ivo Abraham, John Palmer, Jennifer R. Martin, Sandra S. Kramer, Timothy Wunz

Research output: Contribution to journalArticle

417 Citations (Scopus)

Abstract

Background: One approach postulated to improve the provision of health care is effective utilization of team-based care including pharmacists. Objective: The objective of this study was to conduct a comprehensive systematic review with focused meta-analyses to examine the effects of pharmacist-provided direct patient care on therapeutic, safety, and humanistic outcomes. Methods: The following databases were searched from inception to January 2009: NLM PubMed; Ovid/MEDLINE; ABI/INFORM; Health Business Fulltext Elite; Academic Search Complete; International Pharmaceutical Abstracts; PsycINFO; Cochrane Database of Systematic Reviews; National Guideline Clearinghouse; Database of Abstracts of Reviews of Effects; ClinicalTrials.gov; LexisNexis Academic Universe; and Google Scholar. Studies selected included those reporting pharmacist-provided care, comparison groups, and patient-related outcomes. Of these, 56,573 citations were considered. Data were extracted by multidisciplinary study review teams. Variables examined included study characteristics, pharmacists' interventions/services, patient characteristics, and study outcomes. Data for meta-analyses were extracted from randomized controlled trials meeting meta-analysis criteria. Results: A total of 298 studies were included. Favorable results were found in therapeutic and safety outcomes, and meta-analyses conducted for hemoglobin A1c, LDL cholesterol, blood pressure, and adverse drug events were significant (P < 0.05), favoring pharmacists' direct patient care over comparative services. Results for humanistic outcomes were favorable with variability. Medication adherence, patient knowledge, and quality of life-general health meta-analyses were significant (P < 0.05), favoring pharmacists' direct patient care. Conclusions: Pharmacist-provided direct patient care has favorable effects across various patient outcomes, health care settings, and disease states. Incorporating pharmacists as health care team members in direct patient care is a viable solution to help improve US health care.

Original languageEnglish (US)
Pages (from-to)923-933
Number of pages11
JournalMedical care
Volume48
Issue number10
DOIs
StatePublished - Jan 1 2010

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Pharmacists
Meta-Analysis
Patient Care
Databases
Delivery of Health Care
Safety
Patient Care Team
Medication Adherence
Health
Drug-Related Side Effects and Adverse Reactions
PubMed
MEDLINE
LDL Cholesterol
Hemoglobins
Randomized Controlled Trials
Quality of Life
Outcome Assessment (Health Care)
Guidelines
Blood Pressure
Therapeutics

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

US pharmacists' effect as team members on patient care : Systematic review and meta-analyses. / Chisholm-Burns, Marie; Kim Lee, Jeannie; Spivey, Christina; Slack, Marion; Herrier, Richard N.; Hall-Lipsy, Elizabeth; Graff Zivin, Joshua; Abraham, Ivo; Palmer, John; Martin, Jennifer R.; Kramer, Sandra S.; Wunz, Timothy.

In: Medical care, Vol. 48, No. 10, 01.01.2010, p. 923-933.

Research output: Contribution to journalArticle

Chisholm-Burns, M, Kim Lee, J, Spivey, C, Slack, M, Herrier, RN, Hall-Lipsy, E, Graff Zivin, J, Abraham, I, Palmer, J, Martin, JR, Kramer, SS & Wunz, T 2010, 'US pharmacists' effect as team members on patient care: Systematic review and meta-analyses', Medical care, vol. 48, no. 10, pp. 923-933. https://doi.org/10.1097/MLR.0b013e3181e57962
Chisholm-Burns, Marie ; Kim Lee, Jeannie ; Spivey, Christina ; Slack, Marion ; Herrier, Richard N. ; Hall-Lipsy, Elizabeth ; Graff Zivin, Joshua ; Abraham, Ivo ; Palmer, John ; Martin, Jennifer R. ; Kramer, Sandra S. ; Wunz, Timothy. / US pharmacists' effect as team members on patient care : Systematic review and meta-analyses. In: Medical care. 2010 ; Vol. 48, No. 10. pp. 923-933.
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