Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism

Sean P. Farris, Aaron Wolen, Michael F. Miles

Research output: Chapter in Book/Report/Conference proceedingChapter

18 Citations (Scopus)

Abstract

Recent simultaneous progress in human and animal model genetics and the advent of microarray whole genome expression profiling have produced prodigious data sets on genetic loci, potential candidate genes, and differential gene expression related to alcoholism and ethanol behaviors. Validated target genes or gene networks functioning in alcoholism are still of meager proportions. Genetical genomics, which combines genetic analysis of both traditional phenotypes and whole genome expression data, offers a potential methodology for characterizing brain gene networks functioning in alcoholism. This chapter will describe concepts, approaches, and recent findings in the field of genetical genomics as it applies to alcohol research.

Original languageEnglish (US)
Title of host publicationInternational Review of Neurobiology
PublisherAcademic Press Inc.
Pages95-128
Number of pages34
EditionC
DOIs
StatePublished - Jan 1 2010

Publication series

NameInternational Review of Neurobiology
NumberC
Volume91
ISSN (Print)0074-7742

Fingerprint

Neurobiology
Alcoholism
Ethanol
Gene Regulatory Networks
Genomics
Genome
Genetic Loci
Genes
Animal Models
Alcohols
Phenotype
Gene Expression
Brain
Research

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Farris, S. P., Wolen, A., & Miles, M. F. (2010). Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism. In International Review of Neurobiology (C ed., pp. 95-128). (International Review of Neurobiology; Vol. 91, No. C). Academic Press Inc.. https://doi.org/10.1016/S0074-7742(10)91004-0

Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism. / Farris, Sean P.; Wolen, Aaron; Miles, Michael F.

International Review of Neurobiology. C. ed. Academic Press Inc., 2010. p. 95-128 (International Review of Neurobiology; Vol. 91, No. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

Farris, SP, Wolen, A & Miles, MF 2010, Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism. in International Review of Neurobiology. C edn, International Review of Neurobiology, no. C, vol. 91, Academic Press Inc., pp. 95-128. https://doi.org/10.1016/S0074-7742(10)91004-0
Farris SP, Wolen A, Miles MF. Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism. In International Review of Neurobiology. C ed. Academic Press Inc. 2010. p. 95-128. (International Review of Neurobiology; C). https://doi.org/10.1016/S0074-7742(10)91004-0
Farris, Sean P. ; Wolen, Aaron ; Miles, Michael F. / Using Expression Genetics to Study the Neurobiology of Ethanol and Alcoholism. International Review of Neurobiology. C. ed. Academic Press Inc., 2010. pp. 95-128 (International Review of Neurobiology; C).
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