Vaccines and immunomodulatory therapies for food allergy

Jay Lieberman, Anna Nowak-Wȩgrzyn

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

The apparent increase in food allergy prevalence has led to a surge in the amount of clinical and basic science research dedicated to the field. At the current time, allergen avoidance remains the cornerstone of treatment; however, recent clinical trials investigating various forms of immunotherapy have opened doors to the possible future application of an active treatment strategy in everyday practice. In addition, improvements in molecular biology have allowed researchers to purify, clone, and modify allergens, thus laying the groundwork for research on vaccines using modified proteins of decreased allergenicity. Finally, various allergen-nonspecific immunomodulatory therapies are also being investigated as a means to alter the immune response to food allergens. With these emerging therapeutic strategies, it is hoped that practitioners will have options in caring for their food-allergic patients in the near future.

Original languageEnglish (US)
Pages (from-to)55-63
Number of pages9
JournalCurrent Allergy and Asthma Reports
Volume12
Issue number1
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

Fingerprint

Active Immunotherapy
Immunomodulation
Food Hypersensitivity
Allergens
Food
Research
Immunotherapy
Molecular Biology
Therapeutics
Vaccines
Clone Cells
Research Personnel
Clinical Trials
Proteins

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Vaccines and immunomodulatory therapies for food allergy. / Lieberman, Jay; Nowak-Wȩgrzyn, Anna.

In: Current Allergy and Asthma Reports, Vol. 12, No. 1, 01.02.2012, p. 55-63.

Research output: Contribution to journalReview article

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