Vascular ion channels in physiology and disease

Irena Levitan, Alejandro Dopico

Research output: Book/ReportBook

1 Citation (Scopus)

Abstract

Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.

Original languageEnglish (US)
PublisherSpringer International Publishing
Number of pages431
ISBN (Electronic)9783319296357
ISBN (Print)9783319296333
DOIs
StatePublished - Jan 1 2016

Fingerprint

Physiology
Ion Channels
Blood Vessels
Coronary Vasospasm
Tissue
Biological membranes
Intracranial Vasospasm
Ion Transport
Cell proliferation
Medical problems
Vascular Diseases
Pulmonary Hypertension
Tumors
Assays
Brain
Atherosclerosis
Membrane Proteins
Cell Proliferation
Ions
Insulin

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Vascular ion channels in physiology and disease. / Levitan, Irena; Dopico, Alejandro.

Springer International Publishing, 2016. 431 p.

Research output: Book/ReportBook

Levitan, Irena ; Dopico, Alejandro. / Vascular ion channels in physiology and disease. Springer International Publishing, 2016. 431 p.
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