Vascular remodeling and mineralocorticoids

Karl Weber, Yao Sun, S. E. Campbell, S. H. Slight, V. K. Ganjam

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Circulating mineralocorticoid hormones are so named because of their important homeostatic properties that regulate salt and water balance via their action on epithelial cells. A broader range of functions in nonclassic target cellular sites has been proposed for these steroids and includes their contribution to wound healing following injury. A chronic, inappropriate (relative to intravascular volume and dietary sodium intake) elevation of these circulating hormones evokes a wound healing response in the absence of tissue injury — a wound healing response gone awry. The adverse remodeling of vascularized tissues seen in association with chronic mineralocorticoid excess is the focus of this review.

Original languageEnglish (US)
Pages (from-to)533-539
Number of pages7
JournalJournal of Endocrinological Investigation
Volume18
Issue number7
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

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Mineralocorticoids
Wound Healing
Hormones
Dietary Sodium
Wounds and Injuries
Salts
Epithelial Cells
Steroids
Water
Vascular Remodeling

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Vascular remodeling and mineralocorticoids. / Weber, Karl; Sun, Yao; Campbell, S. E.; Slight, S. H.; Ganjam, V. K.

In: Journal of Endocrinological Investigation, Vol. 18, No. 7, 01.01.1995, p. 533-539.

Research output: Contribution to journalArticle

Weber, Karl ; Sun, Yao ; Campbell, S. E. ; Slight, S. H. ; Ganjam, V. K. / Vascular remodeling and mineralocorticoids. In: Journal of Endocrinological Investigation. 1995 ; Vol. 18, No. 7. pp. 533-539.
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