Ventricular tachycardia in fabry disease

Detected in a 50-year-old woman during 14-day continuous cardiac monitoring

Jaime Silva-Gburek, Laura Rochford, Robert Hopkin, John Jefferies

Research output: Contribution to journalArticle

Abstract

Fabry disease is an X-linked lysosomal storage disorder. Female carriers were long thought to be asymptomatic; however, research has revealed the opposite. Cardiac conditions are the chief causes of death in women with Fabry disease. Although ventricular tachycardia has been reported in male patients with Fabry disease, it is not thought to be a frequent finding in females. We describe the case of a 50-year-old woman in whom we used 14-day continuous electrocardiographic monitoring to identify nonsustained ventricular tachycardia, after electrocardiograms and 24-hour Holter monitoring failed to detect the arrhythmia. A permanent implantable cardioverter-defibrillator relieved the patient’s symptoms. We discuss why this case supports the need for more extensive electrophysiologic evaluation in women who have Fabry disease.

Original languageEnglish (US)
Pages (from-to)531-533
Number of pages3
JournalTexas Heart Institute Journal
Volume43
Issue number6
DOIs
StatePublished - Dec 1 2016

Fingerprint

Fabry Disease
Ventricular Tachycardia
Ambulatory Electrocardiography
Implantable Defibrillators
Cardiac Arrhythmias
Cause of Death
Electrocardiography
Research

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Ventricular tachycardia in fabry disease : Detected in a 50-year-old woman during 14-day continuous cardiac monitoring. / Silva-Gburek, Jaime; Rochford, Laura; Hopkin, Robert; Jefferies, John.

In: Texas Heart Institute Journal, Vol. 43, No. 6, 01.12.2016, p. 531-533.

Research output: Contribution to journalArticle

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