Viral Genomic Detection and Outcome in Myocarditis

Neil E. Bowles, Karla R. Bowles, Jeffrey Towbin

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Myocarditis, particularly in children, remains a major cause of morbidity and mortality worldwide. This article discusses diagnosis of viral infection, molecular and alternative diagnostic techniques, association between detection of virus and outcome, and therapeutics of myocarditis. The detection of viral genomic sequences seems to correlate with adverse outcomes in patients who have inflammatory heart muscle disease and treatment regimens that result in viral clearance seem to be effective. Until alternative techniques become available, analysis of endomyocardial biopsy samples for virus and by histology will remain important for the diagnosis and potentially treatment of this disease.

Original languageEnglish (US)
Pages (from-to)407-417
Number of pages11
JournalHeart Failure Clinics
Volume1
Issue number3
DOIs
StatePublished - Oct 1 2005
Externally publishedYes

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Myocarditis
Molecular Diagnostic Techniques
Viruses
Myositis
Virus Diseases
Heart Diseases
Myocardium
Histology
Therapeutics
Morbidity
Biopsy
Mortality

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Viral Genomic Detection and Outcome in Myocarditis. / Bowles, Neil E.; Bowles, Karla R.; Towbin, Jeffrey.

In: Heart Failure Clinics, Vol. 1, No. 3, 01.10.2005, p. 407-417.

Research output: Contribution to journalReview article

Bowles, Neil E. ; Bowles, Karla R. ; Towbin, Jeffrey. / Viral Genomic Detection and Outcome in Myocarditis. In: Heart Failure Clinics. 2005 ; Vol. 1, No. 3. pp. 407-417.
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