XY sex reversal syndrome in the mare

clinical and behavioral studies, H-Y phenotype

Marijo G. Kent, Robert N. Shoffner, Allan Hunter, Keith O. Elliston, Wesley Schroder, Elizabeth Tolley, Stephen S. Wachtel

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

An inherited genetic disorder causes XY embryos of the horse to develop as mares. On the basis of our study of 38 such mares, we have identified four grades or classes of XY sex reversal according to this scheme: class I, nearly normal female, of which some are fertile; class II, female with gonadal dysgenesis, normal mullerian development; calss III, intersex mare with gonadal dysgenesis, abnormal mullerian development, enlarged clitoris; class IV, virilized intersex characterized by high levels of testosterone. In general, class I and calss II mares were typed H-Y antigen-negative whereas class III and class IV mares were typed H-Y antigen-positive.

Original languageEnglish (US)
Pages (from-to)321-328
Number of pages8
JournalHuman genetics
Volume79
Issue number4
DOIs
StatePublished - Aug 1 1988

Fingerprint

H-Y Antigen
Gonadal Dysgenesis
Clitoris
Phenotype
Inborn Genetic Diseases
Horses
Testosterone
Embryonic Structures
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Cite this

Kent, M. G., Shoffner, R. N., Hunter, A., Elliston, K. O., Schroder, W., Tolley, E., & Wachtel, S. S. (1988). XY sex reversal syndrome in the mare: clinical and behavioral studies, H-Y phenotype. Human genetics, 79(4), 321-328. https://doi.org/10.1007/BF00282169

XY sex reversal syndrome in the mare : clinical and behavioral studies, H-Y phenotype. / Kent, Marijo G.; Shoffner, Robert N.; Hunter, Allan; Elliston, Keith O.; Schroder, Wesley; Tolley, Elizabeth; Wachtel, Stephen S.

In: Human genetics, Vol. 79, No. 4, 01.08.1988, p. 321-328.

Research output: Contribution to journalArticle

Kent, MG, Shoffner, RN, Hunter, A, Elliston, KO, Schroder, W, Tolley, E & Wachtel, SS 1988, 'XY sex reversal syndrome in the mare: clinical and behavioral studies, H-Y phenotype', Human genetics, vol. 79, no. 4, pp. 321-328. https://doi.org/10.1007/BF00282169
Kent, Marijo G. ; Shoffner, Robert N. ; Hunter, Allan ; Elliston, Keith O. ; Schroder, Wesley ; Tolley, Elizabeth ; Wachtel, Stephen S. / XY sex reversal syndrome in the mare : clinical and behavioral studies, H-Y phenotype. In: Human genetics. 1988 ; Vol. 79, No. 4. pp. 321-328.
@article{f78657524b634fe6a38be94e1d6b4b1d,
title = "XY sex reversal syndrome in the mare: clinical and behavioral studies, H-Y phenotype",
abstract = "An inherited genetic disorder causes XY embryos of the horse to develop as mares. On the basis of our study of 38 such mares, we have identified four grades or classes of XY sex reversal according to this scheme: class I, nearly normal female, of which some are fertile; class II, female with gonadal dysgenesis, normal mullerian development; calss III, intersex mare with gonadal dysgenesis, abnormal mullerian development, enlarged clitoris; class IV, virilized intersex characterized by high levels of testosterone. In general, class I and calss II mares were typed H-Y antigen-negative whereas class III and class IV mares were typed H-Y antigen-positive.",
author = "Kent, {Marijo G.} and Shoffner, {Robert N.} and Allan Hunter and Elliston, {Keith O.} and Wesley Schroder and Elizabeth Tolley and Wachtel, {Stephen S.}",
year = "1988",
month = "8",
day = "1",
doi = "10.1007/BF00282169",
language = "English (US)",
volume = "79",
pages = "321--328",
journal = "Human Genetics",
issn = "0340-6717",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - XY sex reversal syndrome in the mare

T2 - clinical and behavioral studies, H-Y phenotype

AU - Kent, Marijo G.

AU - Shoffner, Robert N.

AU - Hunter, Allan

AU - Elliston, Keith O.

AU - Schroder, Wesley

AU - Tolley, Elizabeth

AU - Wachtel, Stephen S.

PY - 1988/8/1

Y1 - 1988/8/1

N2 - An inherited genetic disorder causes XY embryos of the horse to develop as mares. On the basis of our study of 38 such mares, we have identified four grades or classes of XY sex reversal according to this scheme: class I, nearly normal female, of which some are fertile; class II, female with gonadal dysgenesis, normal mullerian development; calss III, intersex mare with gonadal dysgenesis, abnormal mullerian development, enlarged clitoris; class IV, virilized intersex characterized by high levels of testosterone. In general, class I and calss II mares were typed H-Y antigen-negative whereas class III and class IV mares were typed H-Y antigen-positive.

AB - An inherited genetic disorder causes XY embryos of the horse to develop as mares. On the basis of our study of 38 such mares, we have identified four grades or classes of XY sex reversal according to this scheme: class I, nearly normal female, of which some are fertile; class II, female with gonadal dysgenesis, normal mullerian development; calss III, intersex mare with gonadal dysgenesis, abnormal mullerian development, enlarged clitoris; class IV, virilized intersex characterized by high levels of testosterone. In general, class I and calss II mares were typed H-Y antigen-negative whereas class III and class IV mares were typed H-Y antigen-positive.

UR - http://www.scopus.com/inward/record.url?scp=0023788476&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023788476&partnerID=8YFLogxK

U2 - 10.1007/BF00282169

DO - 10.1007/BF00282169

M3 - Article

VL - 79

SP - 321

EP - 328

JO - Human Genetics

JF - Human Genetics

SN - 0340-6717

IS - 4

ER -